diff --git a/src/discord/interactions/matrix-info.js b/src/discord/interactions/matrix-info.js
index c85cec2..f5aa539 100644
--- a/src/discord/interactions/matrix-info.js
+++ b/src/discord/interactions/matrix-info.js
@@ -62,7 +62,20 @@ async function _interact({guild_id, data}, {api}) {
 		.sort((a, b) => webGuild._getPosition(a, discord.channels) - webGuild._getPosition(b, discord.channels))
 		.filter(channel => from("channel_room").join("member_cache", "room_id").select("mxid").where({channel_id: channel.id, mxid: event.sender}).get())
 	const matrixMember = select("member_cache", ["displayname", "avatar_url"], {room_id: message.room_id, mxid: event.sender}).get()
-	const name = matrixMember?.displayname || event.sender
+	// Check for per-message profile
+	const perMessageProfile = event.content?.["com.beeper.per_message_profile"]
+	let name = matrixMember?.displayname || event.sender
+	let avatar = utils.getPublicUrlForMxc(matrixMember?.avatar_url)
+	let profileNote = ""
+	if (perMessageProfile) {
+		if (perMessageProfile.displayname) {
+			name = perMessageProfile.displayname
+		}
+		if ("avatar_url" in perMessageProfile) {
+			avatar = perMessageProfile.avatar_url ? utils.getPublicUrlForMxc(perMessageProfile.avatar_url) : undefined
+		}
+		profileNote = " (sent with a per-message profile)"
+	}
 	return {
 		type: DiscordTypes.InteractionResponseType.ChannelMessageWithSource,
 		data: {
@@ -70,9 +83,9 @@ async function _interact({guild_id, data}, {api}) {
 				author: {
 					name,
 					url: `https://matrix.to/#/${event.sender}`,
-					icon_url: utils.getPublicUrlForMxc(matrixMember?.avatar_url)
+					icon_url: avatar
 				},
-				description: `This Matrix message was delivered to Discord by **Out Of Your Element**.\n[View on Matrix →](<https://matrix.to/#/${message.room_id}/${message.event_id}?${via}>)\n\n**User ID**: [${event.sender}](<https://matrix.to/#/${event.sender}>)`,
+				description: `This Matrix message was delivered to Discord by **Out Of Your Element**${profileNote}.\n[View on Matrix →](<https://matrix.to/#/${message.room_id}/${message.event_id}?${via}>)\n\n**User ID**: [${event.sender}](<https://matrix.to/#/${event.sender}>)`,
 				color: 0x0dbd8b,
 				fields: [{
 					name: "In Channels",
diff --git a/src/m2d/converters/event-to-message.js b/src/m2d/converters/event-to-message.js
index 1b23787..7c233c7 100644
--- a/src/m2d/converters/event-to-message.js
+++ b/src/m2d/converters/event-to-message.js
@@ -557,6 +557,18 @@ async function eventToMessage(event, guild, channel, di) {
 	const member = await getMemberFromCacheOrHomeserver(event.room_id, event.sender, di?.api)
 	if (member.displayname) displayName = member.displayname
 	if (member.avatar_url) avatarURL = mxUtils.getPublicUrlForMxc(member.avatar_url)
+	// MSC4144: Override display name and avatar from per-message profile if present
+	const perMessageProfile = event.content["com.beeper.per_message_profile"]
+	if (perMessageProfile?.displayname) displayName = perMessageProfile.displayname
+	if (perMessageProfile && "avatar_url" in perMessageProfile) {
+		if (perMessageProfile.avatar_url === "") {
+			// empty string avatar_url clears the avatar (use default)
+			avatarURL = undefined
+		} else if (perMessageProfile.avatar_url) {
+			// omitted/null falls back to member avatar
+			avatarURL = mxUtils.getPublicUrlForMxc(perMessageProfile.avatar_url)
+		}
+	}
 	// If the display name is too long to be put into the webhook (80 characters is the maximum),
 	// put the excess characters into displayNameRunoff, later to be put at the top of the message
 	let [displayNameShortened, displayNameRunoff] = splitDisplayName(displayName)
@@ -799,6 +811,10 @@ async function eventToMessage(event, guild, channel, di) {
 		if (shouldProcessTextEvent) {
 			if (event.content.format === "org.matrix.custom.html" && event.content.formatted_body) {
 				let input = event.content.formatted_body
+				if (perMessageProfile?.has_fallback) {
+					// Strip fallback elements added for clients that don't support per-message profiles
+					input = input.replace(/<(\w+)[^>]*\bdata-mx-profile-fallback\b[^>]*>[^<]*<\/\1>/g, "")
+				}
 				if (event.content.msgtype === "m.emote") {
 					input = `* ${displayName} ${input}`
 				}
@@ -944,6 +960,10 @@ async function eventToMessage(event, guild, channel, di) {
 			} else {
 				// Looks like we're using the plaintext body!
 				content = event.content.body
+				if (perMessageProfile?.has_fallback && perMessageProfile.displayname && content.startsWith(perMessageProfile.displayname + ": ")) {
+					// Strip the display name prefix fallback added for clients that don't support per-message profiles
+					content = content.slice(perMessageProfile.displayname.length + 2)
+				}
 
 				if (event.content.msgtype === "m.emote") {
 					content = `* ${displayName} ${content}`
diff --git a/src/m2d/converters/event-to-message.test.js b/src/m2d/converters/event-to-message.test.js
index 1c263b4..bc73df7 100644
--- a/src/m2d/converters/event-to-message.test.js
+++ b/src/m2d/converters/event-to-message.test.js
@@ -5526,6 +5526,141 @@ test("event2message: known and unknown emojis in the end are used for sprite she
 	)
 })
 
+test("event2message: com.beeper.per_message_profile overrides displayname and avatar_url", async t => {
+	t.deepEqual(
+		await eventToMessage({
+			type: "m.room.message",
+			sender: "@cadence:cadence.moe",
+			content: {
+				msgtype: "m.text",
+				body: "hello from unstable profile",
+				"com.beeper.per_message_profile": {
+					id: "custom-id",
+					displayname: "Unstable Name",
+					avatar_url: "mxc://maunium.net/hgXsKqlmRfpKvCZdUoWDkFQo"
+				}
+			},
+			event_id: "$g07oYSZFWBkxohNEfywldwgcWj1hbhDzQ1sBAKvqOOU",
+			room_id: "!kLRqKKUQXcibIMtOpl:cadence.moe"
+		}),
+		{
+			ensureJoined: [],
+			messagesToDelete: [],
+			messagesToEdit: [],
+			messagesToSend: [{
+				username: "Unstable Name",
+				content: "hello from unstable profile",
+				avatar_url: "https://bridge.example.org/download/matrix/maunium.net/hgXsKqlmRfpKvCZdUoWDkFQo",
+				allowed_mentions: {
+					parse: ["users", "roles"]
+				}
+			}]
+		}
+	)
+})
+
+test("event2message: com.beeper.per_message_profile empty avatar_url clears avatar", async t => {
+	t.deepEqual(
+		await eventToMessage({
+			type: "m.room.message",
+			sender: "@cadence:cadence.moe",
+			content: {
+				msgtype: "m.text",
+				body: "hello with cleared avatar",
+				"com.beeper.per_message_profile": {
+					id: "no-avatar",
+					displayname: "No Avatar User",
+					avatar_url: ""
+				}
+			},
+			event_id: "$g07oYSZFWBkxohNEfywldwgcWj1hbhDzQ1sBAKvqOOU",
+			room_id: "!kLRqKKUQXcibIMtOpl:cadence.moe"
+		}),
+		{
+			ensureJoined: [],
+			messagesToDelete: [],
+			messagesToEdit: [],
+			messagesToSend: [{
+				username: "No Avatar User",
+				content: "hello with cleared avatar",
+				avatar_url: undefined,
+				allowed_mentions: {
+					parse: ["users", "roles"]
+				}
+			}]
+		}
+	)
+})
+
+test("event2message: data-mx-profile-fallback element is stripped from formatted_body when per-message profile is present", async t => {
+	t.deepEqual(
+		await eventToMessage({
+			type: "m.room.message",
+			sender: "@cadence:cadence.moe",
+			content: {
+				msgtype: "m.text",
+				body: "Tidus Herboren: one more test",
+				format: "org.matrix.custom.html",
+				formatted_body: "<strong data-mx-profile-fallback>Tidus Herboren: </strong>one more test",
+				"com.beeper.per_message_profile": {
+					id: "tidus",
+					displayname: "Tidus Herboren",
+					avatar_url: "mxc://maunium.net/hgXsKqlmRfpKvCZdUoWDkFQo",
+					has_fallback: true
+				}
+			},
+			event_id: "$g07oYSZFWBkxohNEfywldwgcWj1hbhDzQ1sBAKvqOOU",
+			room_id: "!kLRqKKUQXcibIMtOpl:cadence.moe"
+		}),
+		{
+			ensureJoined: [],
+			messagesToDelete: [],
+			messagesToEdit: [],
+			messagesToSend: [{
+				username: "Tidus Herboren",
+				content: "one more test",
+				avatar_url: "https://bridge.example.org/download/matrix/maunium.net/hgXsKqlmRfpKvCZdUoWDkFQo",
+				allowed_mentions: {
+					parse: ["users", "roles"]
+				}
+			}]
+		}
+	)
+})
+
+test("event2message: displayname prefix is stripped from plain body when per-message profile has_fallback", async t => {
+	t.deepEqual(
+		await eventToMessage({
+			type: "m.room.message",
+			sender: "@cadence:cadence.moe",
+			content: {
+				msgtype: "m.text",
+				body: "Tidus Herboren: one more test",
+				"com.beeper.per_message_profile": {
+					id: "tidus",
+					displayname: "Tidus Herboren",
+					has_fallback: true
+				}
+			},
+			event_id: "$g07oYSZFWBkxohNEfywldwgcWj1hbhDzQ1sBAKvqOOU",
+			room_id: "!kLRqKKUQXcibIMtOpl:cadence.moe"
+		}),
+		{
+			ensureJoined: [],
+			messagesToDelete: [],
+			messagesToEdit: [],
+			messagesToSend: [{
+				username: "Tidus Herboren",
+				content: "one more test",
+				avatar_url: undefined,
+				allowed_mentions: {
+					parse: ["users", "roles"]
+				}
+			}]
+		}
+	)
+})
+
 test("event2message: all unknown chess emojis are used for sprite sheet", async t => {
 	t.deepEqual(
 		await eventToMessage({